As our treatment center has a skilled PCI laboratory with an experienced interventional cardiologist on duty 24 h a day, patients admitted to our hospital undergo primary PCI if coronary arteries are suitable, as recommend in current standard guidelines within <90 min door-to-balloon time. Timely reperfusion of the infarct-related coronary artery using fibrinolysis or PCI is central to optimal STEMI treatment. Reperfusion therapy is the cornerstone of treatment for patients with acute ST-elevation myocardial infarction (STEMI). Post-interventional TIMI flow ≤ 2 is strongly associated with adverse out-come during hospitalization and after 6 months following hospitalization. After 6 months, patients without restored normal TIMI flow had worse New York Heart Association functional class (NYHA), and had to undergo repeat coronary angiography more often. A regressions analysis showed that predictors leading to such flow patterns are diabetes ( P = 0.013), pre-hospital fibrinolytic therapy ( P = 0.017), cardiogenic shock ( P = 0.002) and a 3-vessel disease ( P = 0.003). In patients with post-interventional TIMI flow ≤ 2 the left anterior descending coronary artery (LAD) was significantly more often seen as the target vessel (54.3% Vs. 24.3% P = 0.002) and use of intra-aortic balloon pump were all more unlikely (5.8% Vs. 32.9% P < 0.0001), left ventricular ejection fraction was better (51.3 Vs. In this group, in-hospital mortality was significant lower (6.4% Vs. In 430 patients, post-interventional TIMI flow 3 could be established. Methods and resultsīetween 20, 500 patients underwent primary PCI for STEMI. We retrospectively evaluated data from our single center “real world patients” database of patients undergoing primary PCI to determine differences in clinical and angiographic patterns in patients with or without restoring thrombolysis in myocardial infarction (TIMI) flow 3. Growing evidence suggests that poor coronary blood flow after primary percutaneous coronary intervention (PCI) is associated with unfavorable clinical out-come.
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